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Research Publications

List of research publications by Punn Augsornworawat

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DeSouza PA, Ishahak M, Qu X, McCornack C, Annamalai D, Mao DD, Vangipurapu R, Fu Y, Vessoni AT, Cleary RT, Han RH, Augsornworawat P, Woodiwiss T, Agovino D, Sizemore B, Kline J, Borhani-Haghighi M, Chen H, Pugazenthi S, Yano H, Wang T, Batista LFZ, Millman JR, Kim AH. INSM1 governs a neuronal progenitor state that drives glioblastoma in a human stem cell model. Nat Commun. 2025;17(1):31.

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Phankeaw P, Khanaruksombat S, Numprasit W, Jamjuntra P, Augsornworawat P, Warnnissorn M, Thuwajit P, Thuwajit C. Stromal transcriptomics uncover LIF as a key effector in high tumor budding triple-negative breast cancer. Scientific Reports. 2025 Nov 25;45309.

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Phanthaphol N, Somboonpatarakun C, Suwanchiwasiri K, Yuti P, Sujjitjoon J, Augsornworawat P, Baillie GS, Junking M, Yenchitsomanus PT. Enhanced cytotoxicity against cholangiocarcinoma by fifth-generation chimeric antigen receptor T cells targeting integrin αvβ6 and secreting anti-PD-L1 scFv. Journal of Translational Medicine. 2025 Apr 16;23(1):451.

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Thongsin N, Suwanpitak S, Augsornworawat P, Srisantitham J, Saiprayong K, Jenjaroenpun P, Wattanapanitch M. Phenotypic and transcriptomic profiling of induced pluripotent stem cell (iPSC)-derived NK cells and their cytotoxicity against cancers. Stem Cell Research & Therapy. 2024 Dec;15(1):1-8.

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Maestas MM, Ishahak M, Augsornworawat P, Veronese-Paniagua DA, Maxwell KG, Velazco-Cruz L, Marquez E, Sun J, Shunkarova M, Gale SE, Urano F. Identification of unique cell type responses in pancreatic islets to stress. Nature communications. 2024 Jul 2;15(1):5567.

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Schmidt MD, Ishahak M, Augsornworawat P, Millman JR. Comparative and integrative single cell analysis reveals new insights into the transcriptional immaturity of stem cell-derived β cells. BMC genomics. 2024 Jan 24;25(1):105.

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Augsornworawat P, Hogrebe NJ, Ishahak M, Schmidt MD, Marquez E, Maestas MM, Veronese-Paniagua DA, Gale SE, Miller JR, Velazco-Cruz L, Millman JR. Single-nucleus multi-omics of human stem cell-derived islets identifies deficiencies in lineage specification. Nature cell biology. 2023 Jun;25(6):904-16.

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Kitamura RA, Maxwell KG, Ye W, Kries K, Brown CM, Augsornworawat P, Hirsch Y, Johansson MM, Weiden T, Ekstein J, Cohen J. Multidimensional analysis and therapeutic development using patient iPSC–derived disease models of Wolfram syndrome. JCI insight. 2022 Sep 22;7(18):e156549.

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Hogrebe NJ, Maxwell KG, Augsornworawat P, Millman JR. Generation of insulin-producing pancreatic β cells from multiple human stem cell lines. Nature protocols. 2021 Sep;16(9):4109-43.

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Augsornworawat P, Maxwell KG, Velazco-Cruz L, Millman JR. Single-cell transcriptome profiling reveals β cell maturation in stem cell-derived islets after transplantation. Cell reports. 2020 Aug 25;32(8).

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Augsornworawat P, Millman JR. Single-cell RNA sequencing for engineering and studying human islets. Current opinion in biomedical engineering. 2020 Dec 1;16:27-33.

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Velazco-Cruz L, Goedegebuure MM, Maxwell KG, Augsornworawat P, Hogrebe NJ, Millman JR. SIX2 regulates human β cell differentiation from stem cells and functional maturation in vitro. Cell Reports. 2020 May 26;31(8).

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Maxwell KG, Augsornworawat P, Velazco-Cruz L, Kim MH, Asada R, Hogrebe NJ, Morikawa S, Urano F, Millman JR. Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice. Science translational medicine. 2020 Apr 22;12(540):eaax9106.

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Hogrebe NJ, Augsornworawat P, Maxwell KG, Velazco-Cruz L, Millman JR. Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells. Nature biotechnology. 2020 Apr 1;38(4):460-70.

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Augsornworawat P, Velazco-Cruz L, Song J, Millman JR. A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells. Acta biomaterialia. 2019 Oct 1;97:272-80.

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Velazco-Cruz L, Song J, Maxwell KG, Goedegebuure MM, Augsornworawat P, Hogrebe NJ, Millman JR. Acquisition of dynamic function in human stem cell-derived β cells. Stem cell reports. 2019 Feb 12;12(2):351-65.

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Scott EA, Karabin NB, Augsornworawat P. Overcoming immune dysregulation with immunoengineered nanobiomaterials. Annual review of biomedical engineering. 2017 Jun 21;19(1):57-84.

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Yi S, Allen SD, Liu YG, Ouyang BZ, Li X, Augsornworawat P, Thorp EB, Scott EA. Tailoring nanostructure morphology for enhanced targeting of dendritic cells in atherosclerosis. ACS nano. 2016 Dec 27;10(12):11290-303.

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Department of Immunology,

Adulyadejvikrom Building, 11th Floor, 2 Wanglang Road, Bangkok-Noi, Bangkok 10700, Thailand

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